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Hubei Honest Biochemical Co., Ltd. |
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Formestane CAS 566-48-3
Name:Formestane
Synonyms: 4-hydroxy-androst-4-ene-17-dione;4-hydroxy-delta(sub4)-androstenedione
CAS: 566-48-3
MF: C19H26O3
MW: 302.41
Chemical Properties:Off-white crystalline powder
Usage:An antitumor drug. An aromatase inhibitor,antineoplastic, aromatase inhibitor.
Packing:Foil bag as requirred
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ITEMS |
SPECIFICATION |
RESULTS |
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Description |
White or Almost White Crystalline Powder |
white powder |
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Identification |
A.B. |
Positive |
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Assay |
97.0~103.0% |
99.30% |
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Specific Rotation |
+101°~+105° |
+102.6° |
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Loss On Drying |
1.0%max |
0.27% |
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Melting Point |
153~157℃ |
153.0~155.0℃ |
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Organic Volatile Impurities |
meets the requirement. |
Conforms |
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Related Substances |
meets the requirement. |
Conforms |
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Residual Solvents |
meets the requirement. |
Conforms |
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Particle Size |
100% ≤20 microns |
Conforms |
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Conclusion |
The specification conform with USP35 standard |
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Formestane is often used to suppress estrogen production from anabolic steroids or prohormones. It also acts as a prohormone to
4-hydroxytestosterone, an active steroid which displays weak androgenic activity in addition to acting as a mild aromatase
inhibitor.Formestane has poor oral bioavailability and as such is no longer popular as many orally active aromatase inhibitors have been identified. It is selective.
