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Imatinib Mesilate CAS 220127-57-1
Product Description:
Imatinib Mesilate CAS 220127-57-1
Product Name: Imatinib mesylate
Synonyms: 4-[(4-methyl-1-piperazinyl)methyl]-n-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-benzamide monomethanesulfonate;STI-571;IMATINIB BASE(IMA-3);ImatinibMesylate/Gleevec;Imatinib Methanesulfonate, STI-571, CGP-57148B, Glivec,;IMATINIB MESYLATE (IMATINIB METHANESULFONATE);alpha-IMATINIB MESYLATE;Imatinib mesylate(TINIBS )
CAS: 220127-57-1
MF: C30H35N7O4S
MW: 589.71
EINECS: 606-892-3
Imatinib mesylate (also called Gleevec) is a small-molecule inhibitor of the fusion protein Bcr-Abl, the causal agent in chronic myelogenous leukemia.
As an inhibitor of PDGFR, imatinib mesylate appears to have utility in the treatment of a variety of dermatological diseases. Imatinib has been reported to be an effective treatment for FIP1L1-PDGFRalpha+ mast cell disease, hypereosinophilic syndrome, and dermatofibrosarcoma protuberans.
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