Hygromycin B
Product Name: Hygromycin B
Synonyms: Hygromycin B solution,1000ppm;Hygromycin B from Streptomyces hygroscopicus Vetec(TM) reagent grade;UREA 8M SOLUTION PROTEOMICS GRADE;Hygromycin B fromStreptomyces hygroscopicus≥ 90% (HPLC);Hygromycin B solution from Biological Fermentation;HYGROMYCIN B HYDRATE;HYGROMYCIN B, STREPTOMYCES HYGROSCOPICUS;HYGROMYCIN B, STREPTOMYCES SPECIES
CAS: 31282-04-9
MF: C20H37N3O13
MW: 527.52
EINECS: 250-545-5
Chemical Properties White to off-white lyophilized powder
Uses antibacterial, anthelmintic; LD50 ip (rat) 63mg/Kg
Uses Hygromycin B, a selective antibiotic that is effective on most bacteria, fungi and higher eukaryotes, inhibits protein synthesis by interfering with translocation and causing mistranslation at the 70S ribosome
Uses Hygromycin B is an aminoglycoside and a selective antibiotic agent for the hph gene. Hygromycin B inhibits protein synthesis by interfering with translocation and causing mistranslation at the 70S rib osome
Uses Hygromycin B is a trisaccharide aminoglycoside with a terminal cyclitol produced by Streptomyces hygroscopicus, reported by researchers at Eli Lily in the early 1950s. Hygromycin B belongs to the destomycin family of aminoglycosides which contain a unique cyclic structure linking the terminal saccharide. Hygromycin B exhibits broad spectrum antibiotic and anthelmintic activity, and is used as a feed additive for swine and poultry. Hygromycin B inhibits polypeptide synthesis by binding peptidyl-tRNA and preventing translocation by Elongation Factor 2.