Hubei Honest Biochemical Co., Ltd.

Tris Base CAS 77-86-1

Tris Base

Product Name: Tris Base

Synonyms: 1,1,1-tris(hydroxymethyl)-methanamin;1,1,1-tris(hydroxymethyl)-methylamin;1,1,1-tris(hydroxymethyl)methylamine;1,3-Propanediol,2-amino-2-(hydroxymethyl)-;2-amino-2-(hydroxymethyl)-3-propanediol;2-Amino-2-hydroxymethylpropanediol;2-Amino-2-methylol-1,3-propanediol;3-Propanediol,2-amino-2-(hydroxymethyl)-1

CAS: 77-86-1

MF: C4H11NO3

MW: 121.14

EINECS: 201-064-4 

Melting point 167-172 °C(lit.)

Boiling point 219-220 °C10 mm Hg(lit.)

density 1,353 g/cm3

Fp 219-220°C/10mm

storage temp. 2-8°C

solubility H2O: 4 M at 20 °C, clear, colorless

form crystalline

color white

Tris base, also known as THAM, is widely used as a biological buffer or as a component of buffer formulations such as TAE and TBE buffers. Tris has a pKa of 8.06 and is very useful in the biology and biochemistry lab because it has buffering capabilities in the range of the typical physiological pH of most living organisms (pH 7.0-9.0). Tris has been reported to interfere with the activity of a number of enzymes, it should therefore be used carefully when studying proteins.

Uses 1, Tris buffer, only nucleic acids and proteins are widely used as solvents.

2, Tris is used for protein crystal growth under different pH conditions.

3, Tris buffer having a low ionic strength can be used nematode (C. elegans) is formed lamin (lamin) intermediate fibers.

4, Tris is a major component of protein electrophoresis buffer.

5, Tris for the preparation of a surfactant, a vulcanization accelerator, and some drug intermediates.

6, Tris titrated also used as standard.

Chemical Properties White crystalline powder

Uses In the synthesis of surface-active agents, vulcanization accelerators, pharmaceuticals. As emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, leather dressings, textile specialties, polishes, cleaning Compounds, so-called soluble oils. Absorbent for acidic gases. Biological buffer.