Hubei Honest Biochemical Co., Ltd.

Metal Poisoning Treatment Pharmaceuticals Dimercaptosuccinic Acid Dmsa

 

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Dimercaptosuccinic Acid(DMSA)

Dimercaptosuccinic Acid(DMSA) CAS No.:304-55-2

Dimercaptosuccinic Acid(DMSA) Purity: 99%

Dimercaptosuccinic Acid(DMSA) Formula: C4H4O4S2

Dimercaptosuccinic Acid(DMSA) Molecular Weight:180.2033

Dimercaptosuccinic Acid(DMSA) Description: white powder

Dimercaptosuccinic Acid(DMSA) Specification: CP

Dimercaptosuccinic Acid(DMSA) Packing: 1kg/aluminum foil bag   

Use:Dimercaptosuccinic Acid(DMSA) is a important pharmaceutical raw material for medicine of heavy metal poisoning such as plumbum, mercury and so on.

Dimercaptosuccinic Acid(DMSA) 2.min. order quantity: 10g 

Dimercaptosuccinic Acid(DMSA) 3.Payment: Western Union, Moneygram, Paypal.

Dimercaptosuccinic Acid(DMSA) 4.Shipment: EMS, DHL, FedEx

Dimercaptosuccinic Acid(DMSA) 5. Delivery: safe & timely, around 7days after payment.

 

Description:

 

The Dimercaptosuccinic acid, with its CAS registry number 2418-14-6, has the systematic name of 2, 3-disulfanylbutanedioic acid. For being a kind  of white crystalline powder, it is soluble in caustic soda liquid. As to its usage, it is usually applied as the intermediate of sodium dimercaptosuccinate, and it could also be used as the detoxicant and health supplements.

 

Application: 

 

DMSA/Dimercaptosuccinic Acid is indicated for the treatment of lead poisoning in children with blood levelmeasured above 45 µg/dL.The use of DMSA is not approved for prophylactic/prevention of lead poisoning in anticipation of exposure in known lead contaminated environments. Its elimination half-life is 2.5- 3.5 h. DMSA can cross the bloodbrain barrier of mice, but not that of humans, limiting its use to extracting heavy metals from parts of the body other than the central nervous system.

 

Another application for DMSA is for provocation of tissue heavy metals in anticipation of a urine test. This is sometimes called a "challenge" or "provoked" heavy metals test. DMSA is used to help mobilize heavy metals stored in body tissues (and therefore not typically present in the circulation) and increase the excretion of heavy metals in the urine. In a study by Howard Frumkin et al., this sort of test was shown to not reliably provide an indication of past chronic mercury exposure, something it was often used for. A 2004 study by GP Archbold, et al. called the results of a DMSA challenge test "misleading" for the purposes of diagnosing mercury toxicity. Moreover, DMSA share the limitation of extracellular distribution, which makes it unable to cross the cell membrane and chelate heavy metals from intracellular sites.