Hubei Honest Biochemical Co., Ltd.

Orlistat 
Synonyms: (s)-2-formylamino-4-methyl-pentanoic acid (s)-1-[[(2s,3s)-3-hexyl-4-oxo-2-oxetanyl]methyl]-dodecyl ester;Ro-18-0647;
(-)-tetrahydrolipstatin(equivalenttoorlistat);Orlipastat
CAS: 96829-58-2 
MF: C29H53NO5 
MW: 495.73 
Chemical Properties: Off-White Solid 
Usage: An antiobesity agent. A pancreatic lipase inhibitor. Antiobesity agent. Tetrahydrolipstatin (orlistat) is a semi-synthetic derivative of lipstatin, a metabolite isolated from Streptomyces toxytricini. Tetrahydrolipstatin acts as a potent, irreversible inhibitor of pancreatic lipase. 
In vivo, it blocks the absorption of triglycerides while allowing fatty acid absorption. Tetrahydrolipstatin is widely used for the treatment of obesity.
Packing:1kg/foil bag or as required

TESTS Specificatione Results 
Description White or almost crystalline powder White crystalline powder 
Identification IR Conforms 
Specific rotation -33 -35° -34° 
Loss on drying <0.5% 0.35% 
Melting point 42-45℃ 42-44℃
Water <=2.0% 0.25% 
Residual solvents n-hexane<=290ppm n-heptane<=5000ppm 20ppm 1260ppm 
Assay(HPLC) >=96.0%(ON DRY BASIS) 97.4%