Hubei Honest Biochemical Co., Ltd.

Cetilistat

Synonyms:Cetilistat(Alt-962);Cetilstat;2-(Hexadecyloxy)-6-methyl-4H-3,1-benzoxazin-4-one;2-(Hexadecycloxy)-6-methyl-4H-3,1-benzoxazin-4-one;4H-3,1-Benzoxazin-4-one,2-(hexadecyloxy)-6-Methyl-;Xinli orlistat

CAS:282526-98-1

MF: C25H39NO3

MW:401.58

Chemical Properties:Off-white Cryst

Usage:A novel pancreatic lipase inhibitor for the treatment of obesity in both diabetic and non-diabetic patients.

 

Test Items	Specification	Test Results
Appearance	White or almost white crystallime powder	White powder
Loss on drying	≤1.0 %	0.86%
Melting Point	72~76 ℃	73.5-75.2℃
Residue on ignition	≤ 0.5%	0.33%
Related Substances	≤ 1.0 %	0.44%
Heavy Metals (ppm)	≤ 20 ppm	Conformed
Assay	≥ 99 %	99.65%

 

Uses

Cetislim (Cetilistat) is a weight loss drug used in combination with a low calorie diet. It works by blocking a substantial amount of fat from being digested and absorbed into the body. This medicine is classified as a lipase inhibitor and it works directly on the digestive system where it blocks the action of a lipolytic enzyme called lipase. These lipases are what the body uses to digest the fat.

 

However, when this medicine is administered alongside a meal, it binds to the lipases, thereby inhibiting them from breaking down the fat. Fats which are not hydrolyzed are instead excreted in the feces, resulting in increased fecal fat excretion and reduced fat absorption. When used together with a reduced calorie diet, it can help improve weight loss and make it easier for overweight patients to get back in shape, thereby boosting the chances of successful weight loss.